Zinc Pyrithione (ZnPT) | CAS 13463-41-7 | Antifungal Agent
Product Name: Zinc Pyrithione (Pyrithione Zinc)
CAS No.: 13463-41-7
Molecular Formula: Zn(C₅H₄NOS)₂
Appearance: White to cream-colored crystalline powder
Solubility: Limited in water; good solubility in organic solvents
1. Introduction
Zinc pyrithione (CAS 13463-41-7) is an organometallic compound widely used as an antimicrobial, antifungal, and antibacterial agent. It is used in shampoos, soaps, and other cosmetic products aimed at treating and preventing dandruff and dermatological disorders.
Zinc pyrithione has long been established as an effective ingredient in personal care products due to its activity against a broad spectrum of microorganisms. Its use in dermatological products is attributed to low irritation levels and high safety profiles during long-term use, helping to control inflammatory processes on the scalp and improve skin condition.
2. Chemical Structure & Synthesis
The chemical formula of zinc pyrithione is:
Zn(C₅H₄NOS)₂
The zinc ion coordinates with two pyrithione ligands. Synthesis is carried out by reacting appropriate zinc salts with a pyrithione ligand, resulting in a stable complex. The resulting product is characterized by high purity and reproducible properties, which is important for the cosmetic industry.
3. Physicochemical Properties
| Property | Description |
|---|---|
| Appearance | White to cream-colored crystalline powder |
| Solubility | Limited in water; good in organic solvents |
| Antimicrobial Activity | Pronounced activity against fungal and bacterial organisms via disruption of pathogen cell membranes |
4. Applications
| Industry | Application |
|---|---|
| Cosmetic Industry | Shampoos, soaps, conditioners, and scalp lotions for dandruff and seborrheic dermatitis |
| Pharmaceuticals | Topical antimicrobial preparations for fungal skin infections |
| Industrial Manufacturing | Active component in antimicrobial protection systems for coatings and plastics |
5. Conclusion
Zinc pyrithione remains one of the most effective and widely used antimicrobial agents in the cosmetic and pharmaceutical industries. Its high activity against fungal and bacterial microorganisms, combined with formula stability, makes it an indispensable component in skin and hair care products.
