Product Name: Fingolimod Hydrochloride (Fingolimod HCl)
CAS No.: 162359-56-0
Synonyms: FTY720; 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol hydrochloride
Molecular Formula: C₁₉H₃₄ClNO₂
Molecular Weight: 343.93
Purity: ≥99%
Description
Fingolimod, marketed under the brand name Gilenya®, is an immunomodulating drug primarily used for the treatment of relapsing forms of multiple sclerosis (MS). Its effect in patients with primary progressive MS remains unclear. Fingolimod is a sphingosine-1-phosphate (S1P) receptor modulator that sequesters lymphocytes in lymph nodes, preventing their involvement in autoimmune reactions.
Clinical Efficacy
Fingolimod has been reported to reduce relapse rates in relapsing-remitting MS by approximately half over a two-year period.
Additional Application
The drug may also be used in chronic inflammatory demyelinating polyneuropathy (CIDP).