Vitamin B5 (Pantothenic Acid) | Coenzyme A Precursor

Product Name: Vitamin B5 (Pantothenic Acid)
CAS No.: 79-83-4
Molecular Formula: C₉H₁₇NO₅
Structure: Amide of pantoic acid and β-alanine (HO–CH₂–C(CH₃)₂–CH(OH)–CO–NH–CH₂–CH₂–COOH)
Appearance: White crystalline powder
Melting Point: 200–205 °C (with decomposition)
Solubility: Very freely soluble in water (>100 g/L) and glycerol; poorly soluble in ethanol

1. Introduction

Vitamin B5 (Pantothenic Acid) is an essential component of coenzyme A (CoA) and acyl carrier proteins (ACP), involved in lipid, carbohydrate, and steroid metabolism.

Pantothenic acid is widely distributed in food (liver, legumes, whole grains). In cells, it is converted to 4'-phosphopantothenate and then to CoA – the main carrier of acyl groups.

2. Production

Obtained microbiologically (Streptomyces spp.) followed by purification.

3. Properties

• Appearance: White crystalline powder

• Melting Point: 200–205 °C (with decomposition)

• Solubility: Very freely soluble in water (>100 g/L) and glycerol; poorly soluble in ethanol

4. Applications

• Pharmaceuticals and nutraceuticals: B5 deficiency, lipid metabolism disorders, wound healing

• Sports nutrition: Support of energy metabolism

• Cosmetics: Skin and nail regeneration (panthenol – alcohol derivative)

5. Conclusion

Vitamin B5 is a key component of energy and lipid metabolism pathways. The daily requirement for adults is 5 mg; in therapy – up to 10–20 mg.