Vitamin B10 (PABA) | CAS 150-13-0 | Skin Health

Product Name: Vitamin B10 (Para-Aminobenzoic Acid, PABA)
CAS No.: 150-13-0
Molecular Formula: C₇H₇NO₂
Structure: Benzene ring with a carboxyl group at position 1 and an amino group at position 4
Appearance: White to slightly yellowish crystalline powder
Melting Point: 187–189 °C
Solubility: Approximately 10 g/L in water at 20 °C; freely soluble in ethanol and alkaline solutions
Stability: Sensitive to oxidizers and light

1. Introduction

Para-aminobenzoic acid (PABA, Vitamin B10) is a water- and fat-soluble vitamin-like factor involved in folate biosynthesis in microorganisms. It provides photoprotective effects in the skin and improves pigmentation.

PABA is produced by intestinal microflora, but in insufficient amounts. It is used in sunscreens and vitamin complexes to improve skin metabolism. Deficiency does not directly cause characteristic syndromes in humans.

2. Synthesis

Industrial production – nitration of benzoic acid, followed by reduction of the nitro group to an amino group.

3. Properties

• Appearance: White to slightly yellowish crystalline powder

• Melting Point: 187–189 °C

• Solubility: Approximately 10 g/L in water at 20 °C; freely soluble in ethanol and alkaline solutions

• Stability: Sensitive to oxidizers and light

4. Applications

• Cosmetology: UV filter in sunscreens and lotions

• Pharmaceuticals: Component of vitamin preparations with folates

• Biotechnology: Raw material for folic acid synthesis in microorganisms

5. Conclusion

PABA is an important component in cosmetics and folate production. When taken orally in large doses, it may cause skin allergies, so dosage should be moderate.