Succinic Acid | CAS 110-15-6 | Krebs Cycle Metabolite

Product Name: Succinic Acid
CAS No.: 110-15-6
Molecular Formula: C₄H₆O₄
Structure: HOOC–CH₂–CH₂–COOH
Appearance: Colorless crystals or white powder
Melting Point: 185–188 °C
Solubility: Approximately 100 g/L in water at 20 °C; soluble in ethanol and acetone
Stability: Stable in neutral and weakly acidic environments; decomposes in strong alkalis

1. Introduction

Succinic acid is a dicarboxylic alpha-omega acid, an important metabolite of the Krebs cycle, involved in energy metabolism and exhibiting adaptogenic, detoxification, and anti-inflammatory properties.

Succinic acid is synthesized in mitochondria during the oxidative decarboxylation of α-keto acids. Exogenous intake improves tissue oxygen utilization, accelerates recovery after exertion, and reduces the severity of intoxication.

2. Synthesis

Industrial production: ferrocyanide method (oxidative decomposition of pyrolusite) or biotechnological fermentation by mucoraceous fungi.

3. Properties

• Appearance: Colorless crystals or white powder

• Melting Point: 185–188 °C

• Solubility: Approximately 100 g/L in water at 20 °C; soluble in ethanol and acetone

• Stability: Stable in neutral and weakly acidic environments; decomposes in strong alkalis

4. Applications

• Nutraceuticals: Adaptogenic complexes, "energy" dietary supplements (300–600 mg/day)

• Pharmaceuticals: Alcohol intoxication, correction of metabolic disorders

• Cosmetics: Anti-aging and soothing products that stimulate cellular metabolism

5. Conclusion

Succinic acid is a key intermediate metabolite with a wide range of indications. When skillfully combined with B vitamins and antioxidants, it enhances detoxifying and energy effects.