Spermidine | Polyamine | CAS 124-20-9 | Autophagy

Natural polyamine present in all living cells. Activates autophagy and possesses antioxidant effects, improving cellular viability and potentially promoting lifespan extension.
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Product Name: Spermidine
CAS No.: 124-20-9
Molecular Formula: C₇H₁₉N₃
Appearance: White crystalline powder
Solubility: Freely soluble in water, contributing to its bioavailability
Stability: Stable under normal storage conditions but sensitive to prolonged moisture exposure


1. Introduction

Spermidine is a natural polyamine present in all living cells. It activates autophagy and possesses antioxidant effects, improving cellular viability and potentially promoting lifespan extension.

Spermidine is an important biomolecular regulator that helps maintain cellular homeostasis. Research shows that it activates autophagy processes, which is associated with the prevention of age-related disorders and improved cellular function.

2. Chemical Structure & Synthesis

Spermidine is a linear molecule with three amino groups. It can be obtained either through natural synthesis in cells or through chemical synthesis to achieve pharmaceutical purity.

3. Properties

  • Appearance: White crystalline powder

  • Solubility: Freely soluble in water, contributing to its bioavailability

  • Stability: Stable under normal storage conditions but sensitive to prolonged moisture exposure

4. Applications

Used as a nutraceutical supplement to activate autophagy, improve cellular metabolism, and support longevity processes. Used in research aimed at slowing aging and preventing neurodegenerative diseases.

5. Conclusion

Spermidine is a promising biologically active substance capable of activating cellular renewal processes and improving homeostasis, which opens potential for its use in anti-aging therapy and health maintenance.

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