Product Name: Histamine Dihydrochloride
CAS No.: 56-92-8
MF: C₅H₁₁Cl₂N₃
Purity: ≥99%
Appearance: White crystalline powder
Description
Histamine is a biological mediator involved in both physiological and pathological processes. It plays important roles in:
Inflammation
Gastric acid secretion
Immune responses
Smooth muscle contraction
Neurotransmission
Endogenous Production
Endogenous histamine is synthesized in all tissues and is primarily stored in the granules of mast cells or basophils. Historically, histamine is best known as a mediator of allergic reactions and inflammation, but its function as an immunostimulator continues to be studied.
Clinical Applications
Histamine dihydrochloride is used as a topical analgesic for minor muscle and joint pain. It is also being investigated as an orphan drug for adjunctive treatment of acute myeloid leukemia (AML) or malignant melanoma.