Hesperidin | Flavonoid | CAS 520-26-3 | Antioxidant

Product Name: Hesperidin
CAS No.: 520-26-3
Molecular Formula: C₂₈H₃₄O₁₅
Appearance: Yellow to orange crystalline substance
Solubility: Limited water solubility; better soluble in alcoholic solutions
Stability: Relatively stable to light and oxygen when stored properly
Antioxidant activity: High capacity for neutralizing free radicals

1. Introduction

Hesperidin is a flavanone glycoside found in citrus fruits, possessing pronounced antioxidant, anti-inflammatory, and vasodilating properties. Hesperidin improves microcirculation, reduces increased capillary permeability, and helps normalize vascular wall tone, making it an important component in pharmaceutical preparations for the treatment of vascular diseases.

Hesperidin is traditionally used in the therapy of cardiovascular diseases caused by microcirculation disorders. Its anti-inflammatory and antioxidant effects reduce oxidative stress and increased capillary permeability, helping to improve metabolic processes in tissues. The natural origin of hesperidin and its high biocompatibility determine its wide use in pharmacological and dietary products.

2. Chemical Structure & Synthesis

The hesperidin molecule consists of a flavanone core to which a sugar residue (rutinoside group) is attached.

Hesperidin is obtained by extraction from citrus peels, followed by purification and standardization. Chemical modification allows for increased solubility and bioavailability of the active component.

3. Properties

• Appearance: Yellow to orange crystalline substance

• Solubility: Limited water solubility; better soluble in alcoholic solutions

• Stability: Relatively stable to light and oxygen when stored properly

• Antioxidant activity: High capacity for neutralizing free radicals

4. Applications

• Cardiovascular therapy: Improving capillary condition, normalizing blood flow, and reducing inflammatory processes

• Dietary supplements: Support for the cardiovascular system and prevention of oxidative stress

• Cosmetology: Improving skin blood supply and reducing signs of cellulite

5. Conclusion

Hesperidin, as a natural flavonoid, has a wide range of biological activities, including antioxidant, anti-inflammatory, and vasodilating effects. Its use in pharmaceuticals and dietetics helps improve the condition of the cardiovascular system and microcirculation, making it a valuable component of modern therapeutic systems.