Gotu Kola Extract | Centella asiatica | Wound Healing

Product Name: Gotu Kola Extract (Centella asiatica)
Source: Leaves of Centella asiatica (gotu kola)
Active Components: Triterpene saponins (asiaticoside, madecassoside), flavonoids, phytosterols
Standardized Asiaticoside Content: ≥10%
Appearance: Greenish-brown powder
Solubility: Soluble in alcohols and water-alcohol mixtures; partially soluble in water
Stability: Store at room temperature in a dry place

1. Introduction

Gotu kola leaf extract (Centella asiatica) contains triterpene saponins (asiaticoside, madecassoside), flavonoids, and phytosterols. It possesses wound-healing, venotonic, and nootropic effects.

Asiaticoside is the key component. It stimulates collagen synthesis, improves microcirculation, and supports cognitive function.

2. Structure and Production

Asiaticoside: C₄₈H₇₈O₁₉ – triterpene skeleton with three sugar groups.

Production: Maceration of leaves in 50–70% ethanol, filtration, evaporation, and lyophilization.

3. Properties

• Appearance: Greenish-brown powder

• Solubility: Soluble in alcohols and water-alcohol mixtures; partially soluble in water

• Standardized asiaticoside content: ≥10%

• Stability: Store at room temperature in a dry place

4. Applications

• Parenteral and oral venotonics – chronic venous insufficiency

• Wound healing preparations – skin injuries

• Nootropic and anxiolytic agents

5. Conclusion

Gotu kola extract is an effective herbal complex for connective tissue regeneration and venous tone improvement. The optimal dose of asiaticoside is 30–60 mg per day.