Ginkgo biloba Extract | Standardized | Brain Circulation

Product Name: Ginkgo biloba Extract
Source: Leaves of Ginkgo biloba
Standardized Content: 24% flavon glycosides + 6% terpenoid lactones (ginkgolides A, B, C, and bilobalide)
Appearance: Light to dark brown powder
Solubility: Soluble in water and water-alcohol mixtures
Stability: Sensitive to light and moisture; store in sealed containers

1. Introduction

Ginkgo biloba leaf extract is a standardized complex of flavon glycosides (24%) and terpenoid lactones (6%): ginkgolides A, B, C, and bilobalide. It possesses nootropic, vasoactive, and antioxidant effects.

It is used to improve cerebral circulation, prevent dementia, reduce symptoms of cluster headaches, and treat Meniere's syndrome. Flavonoids protect vascular endothelium from oxidative stress; terpenoids reduce platelet aggregation.

2. Components and Production

• Flavon glycosides (e.g., quercetin-3-O-glucoside): C₂₁H₂₀O₁₂

• Ginkgolide A: C₂₀H₂₄O₉ – triterpene lactone with a characteristic "three-loop" skeleton

Production: Maceration or percolation of leaves with 60–70% ethanol, filtration, concentration, standardization for activity, solvent removal, and spray drying.

3. Properties

• Appearance: Light to dark brown powder

• Solubility: Soluble in water and water-alcohol mixtures

• Standardization: 24% flavon glycosides + 6% terpenoid lactones

• Stability: Sensitive to light and moisture; store in sealed containers

4. Applications

• Dietary supplements and pharmaceuticals – cognitive impairment and vascular dementia (120–240 mg/day)

• Peripheral microcirculation disorders – intermittent claudication

• Antioxidant and neuroprotective formulations

5. Conclusion

Ginkgo biloba extract is a proven herbal preparation for improving cerebral and peripheral microcirculation, possessing a comprehensive neuroprotective effect.