Acetyl L-Carnitine (ALCAR) | Nootropic | CAS 3040-38-8

Product Name: Acetyl L-Carnitine (ALCAR)
CAS No.: 3040-38-8
Molecular Formula: C₉H₁₇NO₄
Structure: L-carnitine with an acetyl group on the hydroxyl group
Appearance: White crystalline powder
Melting Point: 162–165 °C (decomposes)
Solubility: Approximately 30 g/L in water at 20 °C; freely soluble in alcohols
Stability: Sensitive to strong alkalis and high temperatures; store in sealed containers

1. Introduction

Acetyl L-carnitine is an acetylated amino acid, a key intermediary for fatty acid transport into mitochondria. Better bioavailability and the ability to cross the blood-brain barrier make it a nootropic and metabolic stimulant.

ALCAR increases acetyl-CoA synthesis, stimulates energy metabolism, improves cognitive function, and protects neurons from oxidative stress. It is recommended for chronic fatigue, cognitive impairment, and cardiovascular support.

2. Synthesis

Acetylation of L-carnitine with acetic anhydride under mild alkaline conditions, followed by purification by crystallization.

3. Properties

• Appearance: White crystalline powder

• Melting Point: 162–165 °C (decomposes)

• Solubility: Approximately 30 g/L in water at 20 °C; freely soluble in alcohols

• Stability: Sensitive to strong alkalis and high temperatures; store in sealed containers

4. Applications

• Nootropic and anti-aging formulations – doses 500–2000 mg/day

• Type 2 diabetes support – improved fat utilization

• Cardioprotectors and post-exercise recovery

• Neuroprotective therapy – dementias

5. Conclusion

Acetyl L-carnitine is an effective metabolic and nootropic agent with a wide range of applications, good tolerability, and a high safety profile.