Heme Iron Polypeptide CAS 16009-13-5

Heme Iron Polypeptide – Highly Bioavailable Iron Source for Dietary Supplements

Basic Information

• CAS Number: 16009-13-5

• Molecular Formula: C₃₄H₃₂ClFeN₄O₄

• Appearance: Violet-black crystals

• Total Iron Content: ≥8.2%

• Assay: ≥95% purity

Overview
Heme iron polypeptide is a natural, highly bioavailable form of iron derived from heme (the iron-containing component of hemoglobin and myoglobin). In the human body, iron is essential for the formation of hemoglobin, which transports oxygen through the blood to tissues and organs, and myoglobin, which helps muscle cells store oxygen for use during physical activity. Unlike non-heme iron (found in plant sources and supplements), heme iron is more efficiently absorbed and better tolerated.

Mechanism of Action
Heme iron is absorbed through a specific transporter in the intestinal mucosa, resulting in higher bioavailability and fewer gastrointestinal side effects compared to inorganic iron salts (e.g., ferrous sulfate). Once absorbed, it is incorporated into hemoglobin and myoglobin, supporting oxygen transport and energy metabolism.

Applications

• Dietary supplements: Used as an iron fortifier in tablets, capsules, powders, and liquid formulations.

• Functional foods: Added to foods and beverages to address iron deficiency.

• Clinical nutrition: Used in specialized nutritional products for patients with iron deficiency anemia.

• Sports nutrition: Supports oxygen delivery and endurance in athletes.

• Pediatric nutrition: Suitable for children's supplements and fortified foods due to its mildness.

Key Benefits

• High bioavailability – better absorbed than non-heme iron salts.

• Gentle on the stomach – fewer gastrointestinal side effects (e.g., constipation, nausea).

• Stable and easy to incorporate into various dosage forms.

• Natural origin – suitable for clean-label and natural products.

• No metallic aftertaste – improves sensory profile of supplements.

Recommended Use
Typical dosage depends on the target iron requirement. For supplementation, common levels range from 5–20 mg of elemental iron per serving. Consult a healthcare professional for specific dosing.

Handling and Storage

• Store in a cool, dry place, protected from light and moisture.

• Keep containers tightly sealed to prevent oxidation and degradation.

• Use standard food-grade handling practices (gloves, protective clothing) when manufacturing.

Packaging
Available in 1 kg, 5 kg, and 25 kg containers. Custom packaging upon request.

Quality Assurance
Each batch is tested for purity, iron content, heavy metals, and microbial contamination to ensure compliance with food and supplement quality standards.