Adenosine 5'-Monophosphate (5'-AMP) CAS 61-19-8

Adenosine 5'-Monophosphate (5'-AMP) – Nucleotide for Food, Pharmaceutical, and Research Applications

Basic Information

• CAS Number: 61-19-8

• Molecular Formula: C₁₀H₁₄N₅O₇P

• Molecular Weight: 347.22 g/mol

• Synonyms: 5'-Adenylic acid, AMP

• Appearance: White or almost white crystalline powder

• Solubility: Slightly soluble in water; insoluble in ethanol

• Packaging: 25 kg per drum

• Storage: Keep in tightly sealed containers, in a cool and dry place

Overview
Adenosine 5'-monophosphate (5'-AMP) is a naturally occurring nucleotide composed of a phosphate group, the sugar ribose, and the nitrogenous base adenine. It is a key intermediate in cellular energy metabolism and serves as a building block for RNA synthesis. In addition to its biological roles, 5'-AMP is widely used in the food, pharmaceutical, and biotechnology industries.

Biological Role
5'-AMP is a nucleotide that plays a central role in energy transfer and signal transduction. It is converted to adenosine diphosphate (ADP) and adenosine triphosphate (ATP), the primary energy currency of the cell. It also acts as a precursor for cyclic AMP (cAMP), a critical second messenger in hormone and neurotransmitter signaling.

Applications

• Pharmaceuticals: Used as a raw material in the synthesis of antiviral and anticancer drugs, as well as in the production of nucleoside analogues.

• Food industry: Added as a flavor enhancer (synergistic with inosine monophosphate, IMP) in soups, sauces, and processed foods to impart umami taste; also used as a nutritional supplement.

• Biotechnology and research: Serves as a substrate for enzymatic assays, a component of cell culture media, and a standard in chromatographic analysis.

• Cosmetics: Used in skin care products for its moisturizing and cell-renewing properties.

• Nutraceuticals: Included in dietary supplements for energy support and athletic performance.

Key Benefits

• Natural nucleotide with essential biological functions.

• Enhances umami flavor in foods (synergistic with IMP and glutamates).

• Biocompatible and safe for human consumption.

• Versatile – applicable in multiple industries.

• Stable when stored under recommended conditions.

Handling and Storage

• Store in tightly sealed containers in a cool, dry place, protected from moisture and direct sunlight.

• Use appropriate personal protective equipment (gloves, safety goggles, dust mask) when handling.

• Avoid inhalation of dust and contact with skin and eyes.

Quality Assurance
Each batch is tested for purity (by HPLC), water content, and heavy metals to ensure compliance with food, pharmaceutical, and research standards.