Vitamin B6 (Pyridoxine) | Coenzyme | Metabolism | CAS 65-23-6

Product Name: Vitamin B6 (Pyridoxine)
CAS No.: 65-23-6
Molecular Formula (Pyridoxine): C₈H₁₁NO₃
Structure: Pyridine ring with methyl, hydroxyl, and hydroxymethyl groups (3-hydroxy-2-methyl-5-(hydroxymethyl)pyridine)
Appearance: Yellow crystals or powder
Solubility: Freely soluble in water (≈50 g/L at 20 °C) and ethanol
Stability: Degrades under UV light and high temperatures

1. Introduction

Vitamin B6 is a group of compounds (pyridoxine, pyridoxal, pyridoxamine) and their phosphate esters (PLP, PMP) that act as coenzymes in amino acid metabolism, neurotransmitter synthesis, and heme production.

Pyridoxine is obtained from food (grains, meat, legumes). It is converted to the active form pyridoxal-5'-phosphate (PLP), which is essential for transamination, decarboxylation of amino acids, and the synthesis of GABA, dopamine, and serotonin.

2. Production

Industrial synthesis – microbiological fermentation or chemical condensation of 2-methyl-3-hydroxypyridine with formaldehyde and ammonia.

3. Properties

• Appearance: Yellow crystals or powder

• Solubility: Freely soluble in water (≈50 g/L at 20 °C) and ethanol

• Stability: Degrades under UV light and high temperatures

4. Applications

• Pharmaceuticals: Therapy of neuropathies, premenstrual syndrome, anemia (in combination with folates and B12)

• Dietetics: Vitamin-mineral complexes

• Cosmetics: Regulation of pigmentation and skin barrier functions

5. Conclusion

Vitamin B6 is an essential water-soluble vitamin coenzyme. The recommended daily intake for adults is 1.3–2.0 mg; for pathological conditions, up to 50–100 mg in a course.