Sucralose | High-Intensity Sweetener | CAS 56038-13-2

Product Name: Sucralose
CAS No.: 56038-13-2
Molecular Formula: C₁₂H₁₉Cl₃O₈
Structure: Sucrose derivative with three chlorine atoms at the 4-, 1'-, and 6'-carbon positions
Sweetness: 600× sweeter than sucrose
Appearance: White crystalline powder
Melting Point: Approximately 125 °C
Solubility: Approximately 0.5 g/mL in water at 20 °C; insoluble in non-polar solvents
Stability: Resistant to heat treatment (up to 180 °C) and a wide pH range (2–8)

1. Introduction

Sucralose is a high-intensity, non-caloric sweetener produced by chlorination of sucrose. It is 600 times sweeter than sucrose, practically not absorbed by the body, and resistant to heat and acids.

Sucralose is widely used in the food industry (beverages, desserts, baked goods) and pharmaceuticals (chewable tablets, syrups) when a sweet taste is desired without additional calories or the risk of tooth decay.

2. Synthesis

Selective multi-step chlorination of sucrose in the presence of protecting groups, followed by deprotection.

3. Properties

• Appearance: White crystalline powder

• Melting Point: Approximately 125 °C

• Solubility: Approximately 0.5 g/mL in water at 20 °C; insoluble in non-polar solvents

• Stability: Resistant to heat treatment (up to 180 °C) and a wide pH range (2–8)

4. Applications

• Food industry: Beverages, confectionery products, yogurts, baked goods

• Pharmaceuticals and dietetics: Low-calorie syrups, chewable tablets

• Cosmetics: Sweet taste in toothpastes and breath fresheners

5. Conclusion

Sucralose is a safe and extremely sweet sugar substitute that retains its properties when heated and in acidic environments, without affecting product caloric content.