Monolaurin | CAS 27215-38-9 | Antimicrobial

Product Name: Monolaurin
CAS No.: 27215-38-9
Molecular Formula: C₁₅H₃₀O₄
Structure: Glycerol linked by an ester bond to a C12 fatty acid (HO–CH₂–CH(OH)–CH₂–O–CO–C₁₁H₂₃)
Appearance: White waxy powder or granules
Solubility: Poorly soluble in water; freely soluble in oils and organic solvents
Melting Point: Approximately 60–65 °C
Stability: Resistant to oxidation; requires antioxidants during storage

1. Introduction

Monolaurin is a monoglyceride of glycerol and lauric acid (C12). It possesses potent antiviral, antibacterial, and antifungal activity by disrupting pathogen lipid membranes. It is used for immune support, cosmetics, and dietary supplements.

Monolaurin is naturally found in breast milk and coconut oil. It is active against enveloped viruses (herpes, influenza), Gram-positive bacteria, and fungi. Preliminary research suggests its role in lowering LDL cholesterol levels and modulating microbiota.

2. Synthesis

Obtained by glycerin esterification of lauric acid, followed by fractional distillation and purification.

3. Properties

• Appearance: White waxy powder or granules

• Solubility: Poorly soluble in water; freely soluble in oils and organic solvents

• Melting Point: Approximately 60–65 °C

• Stability: Resistant to oxidation; requires antioxidants during storage

4. Applications

• Nutraceuticals: Capsules and powders for immune and microbiota support

• Pharmaceuticals: Topical ointments and gels for herpes and fungal infections

• Cosmetics: Antimicrobial formulations for skin and hair care

5. Conclusion

Monolaurin is an effective natural antimicrobial agent that is safe and versatile in application. Combining it with probiotics and lipid carriers to improve delivery and enhance action is promising.