DMDM Hydantoin CAS 6440-58-0

DMDM Hydantoin – Formaldehyde‑Releasing Preservative for Cosmetics

Basic Information

• CAS Number: 6440-58-0

• Chemical Name: 1,3‑Dimethylol‑5,5‑dimethylhydantoin

• Molecular Formula: C₇H₁₂N₂O₄

• Molecular Weight: 188.18 g/mol

• Appearance: White crystalline powder or colorless to pale yellow liquid (depending on grade)

• Solubility: Soluble in water, alcohols, and glycols

Overview
DMDM hydantoin is a well‑established preservative widely used in personal care and cosmetic products. It acts as a formaldehyde donor, slowly releasing small amounts of formaldehyde to provide broad‑spectrum antimicrobial activity against bacteria, fungi, and yeast. This mechanism effectively prevents microbial contamination, extending the shelf life of shampoos, conditioners, lotions, creams, and other aqueous formulations.

Applications

• Shampoos, conditioners, and hair care products.

• Skin care: lotions, moisturizers, sunscreens, and cleansers.

• Makeup: foundations, mascaras, and liquid cosmetics.

• Household products: liquid soaps and cleaning agents.

Key Benefits

• Effective at low concentrations (0.1–0.6%).

• Broad‑spectrum activity against Gram‑positive and Gram‑negative bacteria, fungi, and yeast.

• Compatible with most cosmetic ingredients and surfactants.

• Stable across a wide pH range (3–9).

• Economical and easy to formulate.

Safety and Regulatory

• Approved for use in cosmetics in many countries (including EU, US, and Japan) at specified maximum concentrations.

• Releases formaldehyde at levels considered safe for topical use under regulatory limits.

• May cause sensitization in some individuals; product labels typically advise avoiding contact with broken skin.

• Formaldehyde release is limited to low, controlled levels that provide preservation without compromising safety.

Handling and Storage

• Store in a cool, dry, well‑ventilated area, away from direct sunlight and strong oxidizers.

• Keep containers tightly sealed to prevent moisture absorption and contamination.

• Use appropriate personal protective equipment (gloves, safety goggles) when handling.

Packaging
Available in 25 kg drums, 200 kg drums, and custom packaging upon request.

Quality Assurance
Each batch is tested for purity, formaldehyde release profile, and microbial efficacy to ensure consistent performance.