2-Octyl Cyanoacrylate CAS 133978-15-1

2-Octyl Cyanoacrylate – Medical-Grade Adhesive for Surgical Hemostasis and Wound Closure

Basic Information

• Product Name: 2-Octyl cyanoacrylate

• CAS Number: 133978-15-1

• Molecular Formula: C₁₂H₁₉NO₂

• Purity: ≥99%

• Appearance: Clear, colorless to pale yellow liquid

Overview
2-Octyl cyanoacrylate is a specially formulated medical-grade adhesive monomer designed for use in surgical hemostasis and wound closure. It polymerizes rapidly upon contact with water, moisture, and anionic surfaces (such as biological tissues), forming a strong, flexible, and biocompatible polymer film. This product is widely used as an alternative to traditional sutures and staples, offering faster application, reduced trauma, and excellent sealing properties.

Mechanism of Action
Upon application to tissue, the cyanoacrylate monomer undergoes anionic polymerization initiated by the presence of water or hydroxide ions on the tissue surface. The reaction is rapid (curing within seconds) and mildly exothermic, but well within safe limits for clinical use. The resulting polymer film adheres firmly to the tissue, providing mechanical support, sealing wounds, and controlling bleeding.

Applications

• Surgical hemostasis: Used to control bleeding in surgical procedures by creating a physical barrier and promoting clotting.

• Wound closure: Applied to close incisions, lacerations, and surgical wounds, reducing healing time and scarring.

• Emergency trauma care: Quick application in pre-hospital and emergency settings for bleeding control.

• Veterinary medicine: Used in animal surgery for similar applications.

• Other medical devices: Can be combined with phenol for male vas deferens sterilization procedures.

Key Properties

• Fast polymerization – sets within seconds to minutes.

• High bond strength – provides durable adhesion to tissue.

• Flexible film – accommodates tissue movement without cracking or detachment.

• Biocompatible – meets regulatory standards for medical devices.

• Low toxicity – safe for internal and external use.

• Water-resistant – provides a protective barrier against moisture.

Handling and Storage

• Store in a cool, dry place, away from moisture and heat.

• Keep containers tightly sealed to prevent premature polymerization.

• Use in well-ventilated areas; avoid contact with skin and eyes.

• Shelf life: typically 12–24 months under recommended storage conditions (2–8°C).

Packaging
Available in sterile syringes, vials, or ampoules (1 mL, 5 mL, 10 mL) and bulk quantities for manufacturing. Custom packaging upon request.

Quality Assurance
Each batch is tested for purity (GC), water content, and polymerization time to ensure consistent performance.