Methylene diphenyl diisocyanate (MDI) is a key industrial monomer for polyurethanes. Used in rigid and flexible foams, adhesives, sealants, coatings, and binders. Available as pure MDI (4,4′-isomer) and polymeric MDI (pMDI). Reactive with active hydrogen compounds. CAS 101-68-8 (monomer) / 9016-87-9 (polymeric).