Polyglyceryl-6 Monostearate (PGE-6 MS)

Polyglyceryl-6 Monostearate – Non-Ionic O/W Emulsifier for Cosmetic and Pharmaceutical Formulations

Basic Information

• INCI Name: Polyglyceryl-6 Stearate

• CAS Number: 95461-65-7

• Molecular Formula: C₃₆H₇₂O₁₄

• Molecular Weight: ~728.95 g/mol

• HLB Value: ~11.6 (O/W emulsifier)

• Appearance: White to pale yellow powder or waxy solid

• Solubility: Soluble in oils and organic solvents; dispersible in hot water

• Storage: Store in tightly sealed containers in a cool, dry place, protected from moisture and light

Overview
Polyglyceryl-6 monostearate is a non-ionic surfactant and oil-in-water (O/W) emulsifier produced by the selective esterification of polyglycerin (with six glycerol units) with one molecule of stearic acid. This structure results in a molecule with a pronounced hydrophilic head (polyglycerin chain) and a lipophilic tail (stearate group), providing excellent amphiphilic properties. It is a mild, PEG-free, biodegradable emulsifier derived from renewable plant-based sources.

Key Properties

• Non-ionic – compatible with a wide range of ingredients and pH levels.

• Excellent emulsifying, stabilizing, dispersing, and lubricating abilities.

• Good salt and acid resistance.

• High safety and skin compatibility.

• Provides a creamy, smooth texture with a pleasant sensorial feel.

• Improves spreadability and reduces waxy feel.

• Biodegradable and environmentally friendly.

Applications

• Cosmetics and personal care: Used as a primary or co-emulsifier in O/W emulsions, including creams, lotions, sunscreens, makeup removers, and hair care products. Provides stable, creamy textures and improves skin feel.

• Pharmaceuticals: Employed in topical formulations and ointments as an emulsifier and stabilizer.

• Food industry: Used as an O/W emulsifier in various food products (subject to local regulations).

• Industrial: Applied as a dispersant and stabilizer in coatings, adhesives, and specialty chemicals.

Key Benefits

• Effective O/W emulsification with high stability.

• Mild and non-irritating – suitable for sensitive skin.

• PEG-free and biodegradable – eco-friendly.

• Compatible with a wide range of ingredients.

• Provides creamy, smooth textures with good spreadability.

• Derived from renewable plant-based sources.

• Suitable for challenging formulations, including sunscreens with high loads of UV filters.

Recommended Use
Typical usage levels range from 1–5% of the formulation, depending on the desired emulsion stability and texture. For optimal performance, combine with co-emulsifiers or thickeners as needed. It is easily soluble in hot water and can be incorporated into the oil or water phase during emulsification.

Safety and Handling

• Generally recognized as safe (GRAS) for use in cosmetics and food at recommended concentrations.

• Low irritation potential; well-tolerated by skin and mucous membranes.

• Avoid contact with strong oxidizers and acids.

• Store in a cool, dry place, away from direct sunlight.

• Use appropriate personal protective equipment (gloves, safety goggles) when handling.

Quality Assurance
Each batch is tested for purity, acid value, saponification value, and emulsification performance to ensure consistent quality.