Isopropyl Palmitate CAS 142-91-6

Isopropyl Palmitate – Emollient Ester for Cosmetics and Pharmaceuticals

Basic Information

• CAS Number: 142-91-6

• Molecular Formula: C₁₉H₃₈O₂

• Molecular Weight: 298.50 g/mol

• Appearance: Clear, colorless to slightly yellowish liquid

• Odor: Practically odorless or very faint

• Density: ~0.85 g/cm³ (at 20°C)

• Melting Point: ~13°C

• Boiling Point: ~361°C (at atmospheric pressure)

• Flash Point: ~113°C (closed cup)

• Solubility: Practically insoluble in water; soluble in organic solvents (alcohols, ethers)

• Storage: Store in tightly sealed containers, protected from light and heat, at room temperature

Overview
Isopropyl palmitate is the ester of isopropyl alcohol and palmitic acid, widely used in cosmetic and pharmaceutical formulations. It serves as an emollient and skin conditioning agent, providing a smooth, non-greasy feel. Its lipophilic nature enhances the spreadability of products and facilitates the penetration of active ingredients into the skin. It is compatible with a wide range of oils and other cosmetic ingredients.

Applications

• Cosmetics and personal care: Used in creams, lotions, sunscreens, makeup removers, and hair care products as a skin softener and conditioner.

• Pharmaceuticals: Employed as a penetration enhancer and solubilizer in topical formulations and transdermal patches.

• Industrial: Used as a lubricant, plasticizer, or in specialty emulsions.

Key Benefits

• Excellent skin conditioning and smoothing properties.

• Improves spreadability and product texture.

• Provides a silky, non-oily after-feel.

• Enhances the absorption of active ingredients.

• Stable and compatible with most cosmetic ingredients.

• Cost-effective and widely used in the industry.

Safety and Handling

• Generally recognized as safe (GRAS) for use in cosmetics and topical pharmaceuticals.

• Rarely causes skin irritation; may cause mild reactions in sensitive individuals.

• Avoid contact with strong oxidizers and acids.

• Store in a cool, dry place, away from direct sunlight.

• Use appropriate personal protective equipment (gloves, safety goggles) when handling.

Quality Assurance
Each batch is tested for purity, acid value, saponification value, and color to ensure consistent quality.