Polyglyceryl-2 Caprate (Sesquicaprylate) CAS 50950-12-4

Polyglyceryl-2 Caprate (Polyglyceryl-2 Sesquicaprylate): Overview

1. Chemical Structure

Polyglyceryl-2 sesquicaprylate contains 1.5 to 2 molar equivalents of glycerol residues esterified with caprylic acid, providing simultaneous hydrophilicity (polyol groups) and lipophilicity (alkyl chain). It is a non-ionic surfactant belonging to the polyglyceryl caprate/caprylate class.

INCI name: Polyglyceryl-2 Sesquicaprylate
Probable CAS: 50950-12-4 (common for polyglyceryl caprates)
HLB: ~6–8 (lipophilic, suitable for W/O and O/W emulsions)

2. Physicochemical Properties

Appearance: Semi-transparent substance, from liquid consistency to soft wax

Solubility: Forms stable oil-in-water and water-in-oil emulsions

Density: ~1.05 g/cm³

Storage: Requires protection from moisture to prevent hydrolysis

3. Applications

Emulsion stabilization: Compatible with vegetable and mineral oils; improves stability of both W/O and O/W systems.

Gentle cleansing: Suitable for mild cleansers without excessive skin degreasing.

Cosmetic emulsions: Helps form a pleasant texture without a sticky feel.

Baby care and sensitive skin: Low irritation profile makes it suitable for delicate formulations.

4. Safety and Limitations

Irritation threshold: Very low; suitable for sensitive skin products.

Food use: Permitted in some regions under purity conditions.

Environmental behavior: Degrades under microbiological action; not classified as a persistent pollutant.

5. Conclusion

Polyglyceryl-2 sesquicaprylate is the result of targeted synthesis of mild surfactants for cosmetic and food segments. Its dual character – hydrophilic and lipophilic – provides broad opportunities for developing eco-friendly and skin-comfortable formulations.