Lauryldimethylamine (DMA12) – Tertiary Amine CAS 112-18-5

1227 Customized (Lauryldimethylamine, CAS 112-18-5): Overview

1. Introduction

1227 Customized (Lauryldimethylamine, CAS 112-18-5) is a pure C12 tertiary amine with a dimethylated nitrogen center and a dodecyl (C₁₂) hydrocarbon chain. Its molecular structure combines a hydrophobic alkyl tail with a polar tertiary amine head, providing high surface activity and the ability to form protonated salts, which underlies its functionality in surfactant formulations, corrosion inhibitors, flotation agents, and other industrial products. The compound is also known as N,N-dimethyldodecylamine, dimethyl lauramine, or DDA.

2. Chemical Nature and Properties

Molecular formula: C₁₄H₃₁N (C₁₂H₂₅N(CH₃)₂)

Molecular weight: 213.41 g/mol

CAS number: 112-18-5

EC number: 203-943-8

Appearance: Colorless to light yellow liquid

Melting point: –20°C

Boiling point: 247°C (at atmospheric pressure); 80–82°C at 0.1 mmHg

Density: 0.775–0.799 g/cm³

Flash point: >110°C (combustible)

Solubility: Soluble in organic solvents (alcohols, ketones, hydrocarbons); limited in water, but forms more soluble salts under acidic conditions.

Surface activity: Significantly reduces interfacial tension through micelle formation. When reacted with acids or alkylating agents, it acquires strong cationic properties.

3. Synthesis Methods

Lauryldimethylamine is typically produced by:

• Alkylation of primary amines: Reaction of dodecylamine with formaldehyde and formic acid (reductive methylation) or with methyl halides.

• Hydrogenation of nitriles: Dodecanonitrile is hydrogenated to the primary amine, followed by methylation.

• Catalytic processes: Using nickel or other catalysts for selective methylation.

4. Applications

Quaternary ammonium compounds (QACs): Lauryldimethylamine is the key raw material for the production of dodecyl dimethyl benzyl ammonium chloride (1227), a widely used cationic surfactant with bactericidal, fungicidal, and textile leveling properties.

Corrosion inhibitors: Adsorbs onto metal surfaces, forming a protective layer that prevents contact with aggressive media.

Surfactant intermediates: Used in the manufacture of amine oxides, betaine surfactants, and cationic detergents for cleaning agents and cosmetics.

Flotation agents: Improves selective adhesion to ores and particles in mineral processing.

Antimicrobial formulations: Serves as a precursor for germicides, bactericides, and wood preservatives.

Nanoparticle synthesis: Used as a capping agent in the synthesis of bimetallic nanoparticles (e.g., Au(core)-Pd(shell)).

Epoxy quaternary ammonium surfactants: Used in the synthesis of antibacterial agents.

5. Safety and Toxicology

Skin and eye irritation: Causes severe skin burns and eye damage. Severely irritating to skin and eyes.

Ingestion: Harmful if swallowed.

Environmental toxicity: Very toxic to aquatic life with long-lasting effects.

Handling: Use in well-ventilated areas with appropriate personal protective equipment (gloves, safety goggles). Avoid contact with strong oxidizers.

Storage: Store in tightly sealed containers away from heat and moisture.

Regulatory status: Subject to REACH registration and transport limited quantities (1.0 L liquid / 1 kg solid).

6. Conclusion

1227 Customized (Lauryldimethylamine, CAS 112-18-5) is a versatile C12 tertiary amine that serves as a critical intermediate in the synthesis of cationic surfactants, corrosion inhibitors, and flotation agents. Its long hydrophobic chain and reactive amine center provide high surface activity and enable the production of a wide range of functional derivatives, including quaternary ammonium compounds (1227), amine oxides, and betaines. Quality control, adherence to safety standards, and proper handling are essential to fully realize its potential while minimizing risks to health and the environment.